RUSSELLS VIPER VENOM TIME Meaning and
Definition
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Russell's Viper Venom Time (RVVT) is a term used to refer to a laboratory test that measures the clotting time of human blood plasma when exposed to Russell's viper venom. It is a valuable diagnostic tool in determining the presence or absence of certain blood clotting disorders, particularly lupus anticoagulant, which is an autoimmune disorder characterized by the excessive clotting of blood.
During the RVVT test, a small amount of Russell's viper venom is mixed with the patient's plasma sample and the time taken for clot formation is measured. This is done by observing changes in the optical density of the mixture, to determine the time it takes for a fibrin clot to form. Typically, normal plasma clots within a certain predefined period, and any deviation from this period indicates the presence of abnormalities.
Russell's Viper Venom Time is a highly sensitive and specific test that helps healthcare professionals identify clotting disorders. When the test result is prolonged, it suggests the presence of lupus anticoagulant, which can lead to an increased risk of blood clots and other circulatory problems. By obtaining accurate and timely results, medical practitioners can effectively diagnose and manage patients with clotting disorders, preventing potential complications such as deep vein thrombosis or stroke.
Overall, Russell's Viper Venom Time is an essential laboratory test for evaluating the clotting ability of blood plasma and detecting abnormalities that may indicate the presence of lupus anticoagulant or other clotting disorders.
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