PSEUDOMONIC ACID A Meaning and
Definition
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Pseudomonic Acid A is a natural compound that belongs to a class of antibiotics called pleuromutilins. It is produced by certain strains of bacteria, predominantly Pseudomonas fluorescens. Pseudomonic Acid A exhibits potent antimicrobial activity against various Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pneumoniae.
The compound was first isolated in 1974 and has since attracted significant attention in the field of antimicrobial research. Pseudomonic Acid A functions by inhibiting the protein synthesis machinery in bacteria, particularly at the peptidyl transferase center of the ribosome. This interference prevents the translation of essential proteins required for bacterial growth and survival, ultimately leading to cell death.
Due to its effectiveness against antibiotic-resistant bacteria, Pseudomonic Acid A has found practical applications in the medical field. It is commonly formulated as an ointment or cream for topical use to treat skin infections caused by susceptible strains of bacteria. The compound's unique mechanism of action and low incidence of resistance make it a valuable therapeutic option, particularly in cases where the use of other antibiotics may be limited.
Overall, Pseudomonic Acid A represents an important class of antibiotics that demonstrates promising activity against Gram-positive bacteria. Ongoing research aims to further explore its potential applications and optimize its pharmacokinetic properties for various medical settings.
Common Misspellings for PSEUDOMONIC ACID A
- oseudomonic acid a
- lseudomonic acid a
- -seudomonic acid a
- 0seudomonic acid a
- paeudomonic acid a
- pzeudomonic acid a
- pxeudomonic acid a
- pdeudomonic acid a
- peeudomonic acid a
- pweudomonic acid a
- pswudomonic acid a
- pssudomonic acid a
- psdudomonic acid a
- psrudomonic acid a
- ps4udomonic acid a
- ps3udomonic acid a
- pseydomonic acid a
- psehdomonic acid a
- psejdomonic acid a
- pseidomonic acid a
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