DUBOISINE Meaning and
Definition
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Duboisine is a chemical substance that belongs to the group of tropane alkaloids. It is derived from the plant species Duboisia, primarily found in Australia. This plant contains several alkaloids, with duboisine being one of the prominent ones.
Duboisine is renowned for its potent mydriatic properties, meaning it causes pupil dilation. When administered, the substance acts as a muscarinic antagonist by blocking the actions of acetylcholine in the body. This inhibitory effect on the parasympathetic nervous system leads to dilation of the pupil and results in a condition known as mydriasis.
Due to its mydriatic properties, duboisine has been extensively used in ophthalmology as an eye drop solution. By inducing pupil dilation, it allows for a wider examination of the interior structure of the eye during diagnostic procedures or surgical interventions. Additionally, this alkaloid has also found application in the pharmaceutical industry, particularly in the production of eye medications.
Although duboisine has important medical effects, it should be used with caution and under the supervision of healthcare professionals, as it can also cause certain unwanted side effects. These adverse effects include increased heart rate, dry mouth, blurred vision, and difficulty in controlling body temperature. Moreover, the substance has the potential to be abused due to its hallucinogenic properties, which necessitates strict control measures.
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An alkaloid obtained from duboisea. The sulphate is the salt usually employed as a hypnotic and in the treatment of paralysis agitans in doses of gr. 1/80-1/40 (0.0008-0.0015); it is also used as a mydriatic.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for DUBOISINE
- suboisine
- xuboisine
- cuboisine
- fuboisine
- ruboisine
- euboisine
- dyboisine
- dhboisine
- djboisine
- diboisine
- d8boisine
- d7boisine
- duvoisine
- dunoisine
- duhoisine
- dugoisine
- dubiisine
- dubkisine
- dublisine
Etymology of DUBOISINE
The word "Duboisine" is derived from the surname of Pierre-Jean Robiquet, a French chemist, and the Latin suffix "-ine" which denotes alkaloids. Pierre-Jean Robiquet was the first to isolate the alkaloid Duboisine from the leaves of the Duboisia plant in the early 19th century. The alkaloid was named after him as a way to honor his contribution to its discovery and research.
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