How Do You Spell DEOXYCOFORMYCIN?

1. Deoxycoformycin, also known as pentostatin, is a synthetic purine analog that is used as a medication in the treatment of certain types of cancer. It belongs to the class of drugs known as antimetabolites, which interfere with the growth and proliferation of cancer cells.

   The primary mechanism of action of deoxycoformycin is inhibition of the enzyme adenosine deaminase. Adenosine deaminase plays a crucial role in the degradation of purine nucleosides, particularly adenosine and deoxyadenosine. By inhibiting this enzyme, deoxycoformycin leads to an accumulation of deoxyadenosine triphosphate (dATP) inside cancer cells, leading to increased DNA synthesis inhibition and ultimately cell death.

   Deoxycoformycin is primarily used in the treatment of hairy cell leukemia, a rare type of blood cancer. It has shown significant efficacy in inducing durable remissions, with overall response rates exceeding 80%. Additionally, deoxycoformycin has shown promise in the treatment of other hematologic malignancies, such as T-cell lymphoma and chronic lymphocytic leukemia.

   However, deoxycoformycin is associated with various side effects, including bone marrow suppression, gastrointestinal disturbances, liver function abnormalities, and immune suppression. Therefore, its use requires careful monitoring and consideration of the benefit-to-risk ratio for each individual patient.

   In summary, deoxycoformycin is a medication that inhibits adenosine deaminase and is used in the treatment of hairy cell leukemia and other hematologic malignancies. It works by interfering with DNA synthesis and ultimately inducing cancer cell death.

Common Misspellings for DEOXYCOFORMYCIN

The word "Deoxycoformycin" is a compound term derived from the combination of three different components: "Deoxy-", "coformycin", and "-in".

1. "Deoxy-" is a prefix derived from the Greek word "δεξύς" (dexys), meaning "lacking" or "absence of". In the context of this compound, "deoxy-" implies the absence or alteration of a specific functional group or structure compared to the parent compound.

2. "Coformycin" is a term derived from the root "-cin", which is commonly used to indicate a drug or medicinal compound. The prefix "co-" is likely derived from "coby", which comes from "cobamide" or "cobalt", as the coformycin compound contains a cobalt ion in its structure.

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